Page 34 - Annual Report 2020
P. 34
Anna Sundborger-Lunna, Ph.D.
Cryo-EM and Molecular Cell Biology
SECTION LEADER / ASSISTANT PROFESSOR
“By revealing how mitochondrial cell death is controlled in healthy cells,
we will be able to manipulate and activate this process
in cancer cells.”
Anna Sundborger-Lunna
Veer Bhatt
In the Cryo-EM and Molecular Cell Biology dynamics: (i) endophilin B1, a potential tumor
Section we are studying how membrane-
remodeling proteins assemble into large complexes and regulate fundamental cell events, such as apoptosis, autophagy and mitochondrial dynamics. Several molecular players with membrane-remodeling activity have been implicated in mitochondrial
suppressor involved in a multitude of intracellular membrane trafficking events (Fig. 1); (ii) dynamin family member Drp1, which is required for
fission of the mitochondrial outer membrane (MOM); (ii) Immunity-Related GTPase M (IRGM), an GTPase related to the dynamin super
family critical for autophagy during the innate
SUMMARY
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