Page 18 - Annual Report 2020

Jarrod French, Ph.D.
Nucleotide Metabolism and Drug Discovery
SECTION LEADER / ASSOCIATE PROFESSOR
“Science is about building bridges,
not fences – strong collaborations enable us to bring together a more diverse
team with broader expertise. This gives us the capability to tackle challenging problems that
would be otherwise
intractable.”
Jarrod French
Humberto De Vitto Faisal Aziz Raja Dey
Danushka Arachchige Brian Richardson
Our lab uses an integrative and highly col- receptors use for signal transduction. We take
laborative approach to identify the molec-
ular determinants of protein function and dysfunction in various physiological contexts. We are particularly interested in proteins and protein complexes that regulate metabolic processes such as nucleotide biosynthesis, the discovery and development of immunomodulatory ther- apies, and the mechanisms that certain photo-
a best tool for the job approach, drawing on the broad skill set of our team and the wide array of chemical, biochemical and biophysical techniques at our disposal. The overarching goal of our work is to exploit the knowledge that we obtain in
these fundamental investigations to improve the standard of care for a range of devastating human diseases.
SUMMARY
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