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 64 | THE HORMEL INSTITUTE // UNIVERSITY OF MINNESOTA The Hormel Institute // JULY 1, 2020 – JUNE 30, 2021
PUBLICATIONS
    An Assessment on Ethanol-Blended Gasoline/ Diesel Fuels on Cancer Risk and Mortality.
S. Mueller, G. Dennison & S. Liu. Int J Environ Res Public Health. 18(13): 6930. (2021).
Role of Yes-associated Protein-1 in Gastrointes- tinal Cancers and Hepatocellular Carcinoma.
X. Qian, W. Zhang, H. Yang, L. Zhang, N. Kang & J. Lai. Explor Res Hypothesis Med.; 6(3): 110- 117. (2021).
Nanomaterials for cancer therapy: current prog- ress and perspectives. Z. Cheng, M. Li, R. Dey & Y. Chen. J Hematol Oncol.; 14: 85. (2021).
Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Y. Yang, C. Liu, W. Zhou, W. Shi, M. Chen, B. Zhang, D. Schatz, Y. Hu, B. Liu. Nat Commun.; 12: 2702. (2021).
Control of Breast Cancer Pathogenesis by Histone Methylation and the Hairless Histone Demethylase. M. Trager, B. Sah, Z. Chen, L. Liu. Endocrinology. 162(8): bqab088. (2021).
Structural basis of copper-efflux-regulator-depen- dent transcription activation. W. Shi, B. Zhang, Y. Jiang, C. Liu, W. Zhou, M. Chen, Y. Yang, Y. Hu, B. Liu. iScience. 24(5): 102449. (2021).
Decursinol Angelate Arrest Melanoma Cell Proliferation by Initiating Cell Death and Tumor Shrinkage via Induction of Apoptosis. S.N. Chang, I. Khan, C-G. Kim, S.M. Park, D.K. Choi, H. Lee, B.S. Hwang, S.C. Kang, & J.G. Park.
Int J Mol Sci. 22(8): 4096. (2021).
Structure of the E. coli agmatinase, SPEB. I. Chitrakar, S.F. Ahmed, A.T. Torelli & J.B. French. PLoS One. 16(4). (2021).
ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation.
T. Aikawa, Y. Ren, M-L. Holm, Yan W. Asmann, A. Alam, M.L. Fitzgerald, G. Bu & T. Kanekiyo. Front Neurosci. 15: 647974. (2021).
Creating clear and informative image-based figures for scientific publications. H. Jambor, A. Antonietti, B. Alicea, T.L. Audisio, S. Auer, V. Bhardwaj, S.J. Burgess, J. Ferling, M.A. Gazda, L.H. Hoeppner, et al. PLoS Biol. (3): e3001161. (2021).
Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides. Y-G. Gao, X. Zhai, I. A. Boldyrev, J.G. Molotkovsky, D.J. Patel, L. Malinina & R.E. Brown. J Biol Chem.; 296: 100600. (2021)
Roles of regulator of chromosome condensation 2 in cancer: Beyond its regulatory function in cell cycle. A. Calderon-Aparicio & A.M. Bode. Oncol Rev. 15(1): 525. (2021).
The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma.
M.S. Chesnokov, I. Khan, Y. Park, J. Ezell, G. Mehta, A. Yousif, L. J. Hong, R. J. Buckanovich, A. Takahashi & I. Chefetz (2021) Cancers (Basel). 13(6): 1369. (2021)
Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replica- tion. Y. Li, F. Shi, J. Hu, L. Xie, L. Zhao, M. Tang, X. Luo, M. Ye, H. Zheng, M. Zhou, N. Liu, A.M. Bode, J. Fan, J. Zhou, Q. Gao, S. Qiu, W.Z. Wu,
X. Zhang, W.h. Liao & Y.Cao. NPJ Precis Oncol. 5: 14. (2021).
Crystal structure of the human PRPK–TPRKB complex. J. Li, Xinli Ma, S. Banerjee, H. Chen, W.y. Ma & A.M. Bode. Commun Biol. 4: 167. (2021).
A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes. T.Y. Wang, Q. Liu, Y. Ren, S.K. Alam, L. Wang, Z. Zhu, L.H. Hoeppner, Dehm SM, Q. Cao & R. Yang. Mol Cell.81(10):2246-2260.e12. (2021)
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. Y-F. Wang, Y. Zhang, Z. Lin, H. Zhang, T-Y., Wang, Y. Cao, D.L. Morris, Y. Sheng, X. Yin, S-L. Zhong, X. Gu, Y. Lei, J. He, et al. Nat Commun. 12: 772. (2021).
Targeting the signaling in Epstein–Barr virus- associated diseases: mechanism, regulation, and clinical study. Y. Cao, L. Xie, F. Shi, M. Tang, Y. Li, J. Hu, L. Zhao, L. Zhao, X. Yu, X. Luo, W.h. Liao, & A.M. Bode. Signal Transduct Target Ther. 6: 15. (2021).
Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence. X. Chen, J. Gu, A.F. Neuwald, L. Hilakivi-Clarke, R. Clarke, J. Xuan. Sci Rep. 11(1):385. (2021).
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). R. Clarke, et al . Autophagy.17(1):1-382. (2021).
ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach.
X. Chen, X. Shi X, A.F. Neuwald AF, Hilakivi- Clarke L, R. Clarke, & J. Xuan. BMC Bioinformat- ics. 22(1):193. (2021).
Emerging roles of dehydrogenase/reductase member 2 (DHRS2) in the pathology of disease. Z. Li, H. Liu, A.M. Bode, & X. Luo. Eur J Pharma- col. 5;898:173972. (2021).
Induction and Detection of Necroptotic Cell Death in Mammalian Cell Culture. M. Chesnokov, I. Khan & I. Chefetz. Methods Mol Biol.2255: 119-134. (2021).
Visualization of Necroptotic Cell Death through Transmission Electron Microscopy. N. Golla,
L. Hong & I. Chefetz. Methods Mol Biol. 2255:135-147. (2021).
Experimental models of endocrine responsive breast cancer: strengths, limitations, and use. R. Clarke R, B.C. Jones, C.M. Sevigny, L. Hilakivi-Clarke, & S. Sengupta. Cancer Drug Resist. 4:762-783. (2021).
A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes. Wang TY, Liu Q, Ren Y, Alam SK, Wang L, Z. Zhu, L.H. Hoeppner, S.M. Dehm, Q. Cao & R. Yang.Mol Cell. 20;81(10):2246-2260. (2021).
Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C-C Motif Chemok- ine Ligand 2-Mediated Angiocrine Signaling.
J. Gao, B. Wei, M. Liu, P. Hirsova, T.S. Sehrawat, S. Cao, X. Hu, F. Xue, U. Yaqoob, N. Kang et al. Hepatology. 73(6):2468-248. (2021).
Role of Yes-associated Protein-1 in Gastrointes- tinal Cancers and Hepatocellular Carcinoma.
X. Qian, W. Zhang, H. Yang, L. Zhang L, N. Kang, J. Lai J.Explor Res Hypothesis Med.;6(3):110- 117. (2021).
Amphipathic Motifs Regulate N-BAR Protein Endophilin B1 Auto-inhibition and Drive Mem- brane Remodeling. S. Veer S Bhatt, R. Ashley & A. Sundborger-Lunna. 7;29(1):61-69.e3. (2021).
Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function. H. De Vitto, J. Ryu,
A. Calderon-Aparicio, J. Monts, R. Dey, A. Chakraborty, M-H. Lee & A.M. Bode. Cancer Metab.; 8: 28. (2020).
Chidamide increases the sensitivity of refractory or relapsed acute myeloid leukemia cells to anthracyclines via regulation of the HDAC3 -AKT-P21-CDK2 signaling pathway. H. Wang, Y-c., Liu, C-y. Zhu, F. Yan, M-z. Wang, X-s.
Chen, X-k. Wang, B-x. Pang, Y-h. Li, D-h. Liu, C-j. Gao, S. Liu, L-p. Dou. J Exp Clin Cancer Res.; 39: 278. (2020).
DIPG-05. Histone H3.3 K27M Impairs SER31 Phosphorylation, Resulting in Chromosomal Instabiity, Loss of Cell Cycle Checkpoint Control, and Tumor Formation. C. Day, A. Langfald, F. Grigore, S. Fadness, L. Sepaniac, J. Stumpff, K. Vaughan, J. Robinson & E. Hinchcliffe. Neuro Oncol. Dec; 22(Suppl 3): iii288. (2020).
Structural basis for multifunctional roles of human Ints3 C-terminal domain. J. Li, X. Ma,
S. Banerjee, S. Baruah, N.J. Schnicker, E. Roh, W. Ma, K. Liu, A.M..Bode. J Biol Chem. Jan-Jun; 296: 100112. (2020).
Suppressing STAT3 activity protects the endo- thelial barrier from VEGF-mediated vascular permeability. L. Wang, M. Astone, Sk. Alam,
Z. Zhu, W. Pei, D.A. Frank, S.M. Burgess & L.H. Hoeppner. Version 3. bioRxiv. (2020).
Effects of leptin on the viability of MCF-7 and T47D cells at different glucose concentrations. P. Demirel, S. Dogan, U. Ozorhan, B. Tuna,
T.F. Schuster, M.P. Cleary. J Exp Clin Med (Samsun). 37(4): 119-125. (2020).
Yes-associated protein-1 may serve as a diagnos- tic marker and therapeutic target for residual/ recurrent hepatocellular carcinoma post-transar- terial chemoembolization. X. Qian, W. Zhang, A. Shams, K. Mohammed, A.S. Befeler, N. Kang & J. Lai. Liver Res. 4(4): 212-217. (2020).













































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